Do all Phosphodiesterase Inhibitors generic names end in “fil”?

The short answer is that unfortunately no, not all phosphodiesterase inhibitors end in “fil”. For instance, aminophylline, theophylline, milrinone are but only a few phosphodiesterase inhibitors with different names. That being said, most of these medications are not used routinely in the community (if at all) nor are they used for erectile dysfunction (ED).

While sildenafil, tadalafil, vardenafil, and the newer udenafil and avanafil all are medications ending in “fil” and do have indications for erectile dysfunction (ED), it may be somewhat risky to rely upon the suffix only to identify this class of medications. For instance, the ace inhibitor class (ramipril, lisinopril. enalapril, captopril) all end with a similar suffix and this could be confusing.

The best approach is to recognize the full name of the medication, then confirm with the patient why they are taking it and the timing of the last dose.