asked 3 days ago
According to the companion document, avoiding Gravol in cases of head injury is recommended, as it may contribute to increased intracranial pressure (ICP). However, I am unable to find supporting documentation explaining how Gravol leads to increased ICP. Could you please clarify this mechanism?
1 Answers
answered 2 days ago
Thank you for your question. I agree that dimenhydrinate’s effect on ICP is not well documented in literature review. Dimenhydrinate can have effects on blood pressure which I would assume could increase ICP. Realistically, the reason I would avoid this medication in head injured patients is because of the sedative effects. When assessing a head injured patient, it is important to have them as alert as possible, giving them dimenhydrinate may make neurological assessment more difficult. For this reason, I would encourage ondansetron in this population.
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