Ask Mac – Questions ListCategory: AnalgesiaOpinion on co-administration of Tylenol and Ibuprofen with opioids.
asked 9 months ago

With some studies showing lower doses of opioids needed with co-administration of a NSAID or Tylenol and ibuprofen. Would this be beneficial practice in the field?

1 Answers
answered 9 months ago
Great question. The co-administration of acetaminophen and/or ibuprofen (NSAID) with an opioid has been shown in several studies to reduce the opioid utilization and maintain effective pain control. Quite often some of the most severe acute pain conditions we treat (ie. Renal Colic) can be reduced significantly with a single dose of NSAID. Many of these patients who present via EMS having received an NSAID en-route will often require no further immediate pain (opioid) medication administered in the emergency department.  
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