Ask Mac – Questions ListCategory: MedicationsDiluting Diphenhydramine
asked 2 years ago
The Benadryl Medication Reference states "Benadryl given IV should be diluted with 9 ml of Normal Saline prior to administration" yet the ALS protocol makes no mention of diluting the medication like it does for Gravol.  Which is the correct way to administer Benadryl IV?
1 Answers
answered 2 years ago

DiphenHYDRAMINE (Benadryl) IV ADMINISTRATION - Administer undiluted or diluted in 10 mL with NS. Give at a maximum rate of 25 mg/min.
2021 The Ottawa Hospital Parenteral Drug Therapy Manual, Forty-Second Edition