Is it safe to give PO Dexamethasone from a vial that says IM/IV only?

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asked 2 years ago

On the vials of Dexamethasone my service has it says for IV/IM use only. Is it safe to administer this PO or should we have another type of Dexamethasone on board for PO administration?

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answered 2 years ago

Thank you for the question on whether IV/IM Dexamethasone can be given orally. The quick answer is yes. IV/IM dexamethasone formulation has been given via the oral route for years in the ED. Below is a link to a paper describing the bioavailability when this formulation is given PO. IV Dexamethasone Given Orally