Ask Mac – Questions ListCategory: BronchoconstrictionIs it safe to give PO Dexamethasone from a vial that says IM/IV only?
asked 4 months ago
On the vials of Dexamethasone my service has it says for IV/IM use only.  Is it safe to administer this PO or should we have another type of Dexamethasone on board for PO administration? 
1 Answers
answered 4 months ago
Thank you for the question on whether IV/IM Dexamethasone can be given orally. The quick answer is yes.  IV/IM dexamethasone formulation has been given via the oral route for years in the ED. Below is a link to a paper describing the bioavailability when this formulation is given PO.  IV Dexamethasone Given Orally